Watch out for pregnancy pitfalls after 40
Many of today’s women are delaying childbearing until later in life for a  variety of reasons, including career choices, financial status, late marriage  and remarriage. In addition, successful treatment of previously infertile women  over 40 is on the rise. In fact, reports indicate successful pregnancies in  women over 60!
While such cases raise complex social and ethical issues  (not to mention medical issues), the fact of the matter is that more women over  40 are choosing to start a new family or add to their present one.
Of  course, for some women, it’s not a matter of choice. Unplanned pregnancies  account for a large proportion of babies born to women over 40.  What risks do  these women incur?  Let’s examine the facts regarding pregnancy in this age  group and strategies to reduce the risks.
The  facts
 
Standard medical teaching indicates a higher risk for  pregnancy complications in women over 35.  These complications can be  categorized as follows:
- Medical illnesses affecting the mother and fetus
- Genetic abnormalities and birth defects
- Pregnancy loss
- Complications of labor and delivery
As age increases beyond 35, so does each of these risks. Nevertheless, proper  preparation before pregnancy and early prenatal care can help assure the best  outcome.
 
Maternal and child  illnesses
 
Certain medical conditions occur more frequently in  pregnant women over 40, including diabetes, high blood pressure and thyroid  disorders.  Fortunately, these conditions can be diagnosed and controlled prior  to pregnancy, and many of the medications used to treat these disorders can be  safely used during pregnancy.  If you currently take medication and you are  planning a pregnancy, talk to your doctor.  A change in medication or an  adjustment of dosage may be necessary.
If not properly treated, maternal  illnesses can adversely affect the fetus.  Uncontrolled high blood pressure can  restrict fetal growth and in severe cases, can result in stillbirth.   Undiagnosed diabetes can carry with it a higher risk of birth defects, and poor  blood-sugar control during pregnancy can result in abnormal fetal growth.  Early  prenatal care and judicious use of medication can lower these risks  significantly.
 
Genetic defects
 
It is an  unfortunate but incontrovertible fact that as a woman ages, a higher proportion  of her eggs contain chromosomal abnormalities.  At the present time, some  infertility centers have the technology to weed out these abnormal eggs, but for  the majority of women who become pregnant after 40, the risk of a genetic defect  increases based on age.
While the general population of childbearing  women has a 3 percent chance of delivering a child with a birth defect, after 40  this risk rises to between 6 percent and 8 percent.  The likelihood of having a  baby with Down’s syndrome is approximately 1 in 365 at the age of 35. This  number increases to 1 in 100 by 40 and up to 1 in 40 at the age of  45.
Pregnancy loss
 
Pregnancy loss also increases  with advancing age. Approximately 50 percemt of early (first trimester)  miscarriages are due to genetic abnormalities of the fetus. Overall, pregnant  women experience miscarriage 15 percent of the time.  After 40, this incidence  nearly doubles.  There is also a moderate increase in stillbirths after 40 due  to a combination of medical complications affecting pregnancy and lethal birth  defects.
 
Complications of labor and  delivery
 
Complications of labor and delivery that are seen  more frequently in women over 40:
- Premature labor
- Premature separation of the placenta resulting in hemorrhage
- Placenta previa (abnormal placement of the placenta over the opening of the cervix)
- Meconium-stained amniotic fluid (fetal waste in the amniotic fluid which can be harmful if breathed in at birth)
- Postpartum hemorrhage
- Malpresentations (breech or other positions other than head down)
As a result, the rate of Cesarean section is considerably higher in this age  group.
 
Lowering the risks
 
Although the  risks associated with pregnancy after 40 are numerous and sometimes unavoidable,  there are several strategies that women over 40 can use to reduce these  risks.
 
See your doctor 
First and foremost, make  an appointment to see your doctor BEFORE you get pregnant.  This  “pre-conception” visit will give your doctor the opportunity to diagnose and  treat any disorders that might otherwise go undetected prior to the initial  prenatal visit.
A thorough evaluation prior to pregnancy will allow  your doctor to give you an idea of your individual risk.  There may be cases in  which pregnancy will be ill-advised.  However, for the majority of women over  40, early prenatal care and good health habits will result in a healthy baby and  a happy mother.
 
Get healthy 
The idea is to be as  healthy as you can BEFORE you get pregnant.  Here are some tips:
- If you smoke, quit.
- Avoid alcohol – alcohol can increase the risk of certain birth defects and interfere with proper fetal growth.
- Avoid caffeine – even moderate caffeine intake might increase your risk of miscarriage (although this remains controversial).
- Eat a well-balanced diet – this means one that is rich in fruits, vegetables, whole grains and low-fat dairy and other protein sources. If you need help, ask your doctor for a referral to a registered dietitian.
- Start a prenatal vitamin prior to pregnancy and stick with it. The folic in prenatal vitamins is known to reduce certain birth defects and the iron supplement will combat anemia.
- Exercise regularly, but moderately. Exercise is good for toning muscles and limbering joints, thereby decreasing the normal aches and pains associated with pregnancy. If you don’t exercise already, check with your doctor before starting an exercise program.
Get tested
If you are concerned about the risk of genetic defects, ask your doctor about tests that can help identify these types of problems. Blood tests are available to screen for some genetic disorders; a “triple screen” blood test may be obtained to evaluate the risk of neural tube defects and Down’s syndrome.
Genetic amniocentesis or chorionic villus sampling is routinely offered to women after 35. Amniocentesis is usually done in the third or fourth month of pregnancy and involves removal of amniotic fluid from the womb for genetic testing. There is a minimal (0.5 percent) risk of miscarriage associated with this test. This risk is outweighed however by the slightly larger risk of having an undetected abnormality.
Chorionic villus sampling can be done earlier in pregnancy and involves the removal of a minute amount of placental tissue, which can then be tested for genetic abnormalities. Discuss the risks and benefits of these tests with your doctor early on so you will have ample time to make an informed decision.
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